Výzkum - Publikace - Původní články

Bubeník J., Krchňák V., Indrová M., Hamšíková E., Jandlová T., Šímová J., Kieler J.:
Localization of a receptor binding site on the IL-2 molecule.
Folia Biologica (Praha) 33, 266 81, 1987.
PMID: 2444471

Suchánková A., Ritter O., Hirsch I., Krchňák V., Kaloš Z., Hamšíková E., Břicháček B., Vonka V.:
Presence of antibody reactive with synthetic peptide derived from L2 open reading frame of human papillomavirus types 6b and 11 in human sera.
Acta Virol. 34, 433 42, 1990.
PMID: 1705748

Suchánková A., Krchňák V., Vágner J., Hamšíková E., Krčmář M., Ritterová L., Vonka V.:
Epitope mapping of the human papilloma virus type 16 E4 protein by means of synthetic peptides.
J. Gen. Virol. 73, 429 32, 1991.
PMID: 1371544

Suchánková A., Krčmář M., Krchňák V., Hamšíková E., Kaňka J., Vágner J., Vonka V.:
Range of HPV16 E7 antibodies in cervical cancer patients and healthy subjects.
Int. J. Cancer 51, 837 8, 1992.
PMID: 1612789

Boštík P., Hofmannová V., Kitasato H., Hamšíková E., Vonka V:
An easy-to-prepare, highly efficient antigen for cervical cancer serology.
Int. J. Cancer 58, 1-2, 1994.
PMID: 8077064

Anisimová E., Barták P., Hamšíková E., Vonka V:
Comparative sensitivity of the immunoelectronmicroscopy test and ELISA with intact virions in detecting HPV-1 antibodies and age distribution of these antibodies among general population and in children‘s homes.
Arch. Virol. 137, 157-60, 1994.

Hamšíková E., Novák J., Hofmannová V., Muňoz N., Bosch FX., de Sanjosé S., Shah K., Roth Z., Vonka V.:
Presence of antibodies to seven human papillomavirus type 16-derived peptides in cervical cancer patients and healthy controls.
JID 170, 1424-31, 1994.
PMID: 7995981

Tachezy R., Van Ranst M., Cruz Y., Burk RD.:
Identification of novel human papillomavirus sequences by consensus primer mediated polymerase chain reaction.
Biological and Biochemical Research Communications 204, 820-827, 1994.
PMID: 7980548

Valvoda J., Tachezy R., Hamšíková E., Betka J., Klozar J.:
Průkaz lidských papillomavirů (HPV) a HPV specifických protilátek u pacientů s recidivující laryngeální papilomatózou.
Otorinolaryngology 43, 184-189, 1994.

Tachezy R., Hamšíková E., Valvoda J., Van Ranst M., Betka J., Burk RD, Vonka V.:
Antibody response to a synthetic peptide derived from the human papillomavirus type 6/11 L2 protein in recurrent respiratory papillomatosis.
J. Med. Virol. 42, 52-59, 1994.
PMID: 8308521

Tan CT, Tachezy R., Van Ranst M., Chan SY., Bernard HU., Burk RD.:
The Mastomys natalensis papillomavirus: Nucleotide sequence, genome organization, and phylogenetic relationship of a rodent papillomavirus involved in tumorigenesis of cutaneous epithelia.
Virology 198, 534-41, 1994.
PMID: 8291235

Ho G., Burk RD., Klein S., Kadish AS., Chang CJ., Palan P., Basu J., Tachezy R., Lewis R., Romney S.:
Persistent genital human papillomavirus infection in the natural history of cervix dysplasia.
JNCI 87, 1365-1371, 1995.
PMID: 7658497

Wadler S., Burk RD., Neuberg D., Rameau R., Runowicz CD., Goldberg G., McGill F., Tachezy R., Comis R., Edmonson J., Wiernik PH.:
Lack of efficacy of interferon-alpha therapy in recurrent, advanced cervical cancer.
J. Int. Cyt. Res. 15, 1011-1016, 1995.
PMID: 8746781

de Sanjose S., Hamšíková E., Muňoz N., Bosch FX., Hofmannová V., Gili M., Izarzugaza I., Viladiu P., Tormo MJ., Moreo P., Muňoz MT., Ascunce N., Tafur L., Shah KV., Vonka V.:
Serological response to HPV16 in CIN III and cervical cancer patients.
Case-control studies in Spain and Colombia. Int. J. Cancer 66, 70-4, 1996.
PMID: 8608970

Kitasato H., Vonka R., Boštík P., Hamšíková E., Sobotková E., Šmahel M., Vonka V.:
Properties of syrian hamster cells transformed by human papillomavirus type 16.
Acta Virol. 40, 281-8, 1996.
PMID: 9171456

Hamšíková E., Šmahel M., Sapp M., Muňoz N., Bosch FX., Shah KV., Vonka V.:
Correlation between the presence of anti HPV33 VLP antibodies and HPV DNA in cervical neoplasia patients.
Arch. Virol. 142, 413-6, 1997.
PMID: 9125054

Viladiu P., Bosch FX., Castellsague X, Muňoz N., Escriba J.M., Hamšíková E., Hofmannová V., Guerrero E., Izquierdo M., Navarro C., Moreo P., Izarzugaza I., Ascunce N., Gili M., Muňoz MT., Tafur L., Shah KV., Vonka V.:
Human papillomavirus DNA and antibodies to human papillomavirus 16 E2, L2 and E7 peptides as predictors of survival in patients with squamous cell cervical cancer.
J. Clin. Oncol. 15, 610-9, 1997.
PMID: 9053484

Hamšíková E., Ludvíková V., Šmahel M., Sapp M., Vonka V.:
Prevalence of antibodies to human papillomaviruses in the general population of the Czech Republic.
Int. J. Cancer 77, 689-94, 1998.
PMID: 9688300

Vonka V., Sobotková E., Hamšíková E., Šmahel M., Žák R., Kitasato H., Sainerová H.:
Induction of antitumour immunity by suicide-gene-modified HPV16-transformed hamster cells.
Int. J. Cancer 77, 470-5, 1998.
PMID: 9663613

Tachezy R., Mikyšková I., Saláková M., Van Ranst M.:
Correlation between human papillomavirus-associated cancer and p53 codon 72 arginine/proline polymorphism.
Human Genetics 105, 564-566, 1999.
PMID: 10647890

Švec A., Urban M., Mikyšková I., Tachezy R.:
HPV in the epididymis detected by PCR method.
Am. J. Surg. Pathol. 23, 1437-1438, 1999. PMID: 10555017

Hamšíková E., Šrámková I., Loudová M., Ludvíková V., Rob L., Vonka V.:
The frequency of HLA–DRB1 and –DQB1 alleles in cervical cancer cases in the Czech Republic.
Folia Biologica (Praha) 45, 217-20, 1999. PMID: 10732716

Vonka V., Hamšíková E., Kaňka J., Ludvíková V., Sapp M., Šmahel M.:
Prospective study on cervical neoplasia. IV. Presence of HPV antibodies.
Int. J. Cancer 80, 365-8, 1999. PMID: 9935175

Rob L., Pluta M., Citterbart K., Robová H., Kačírek J., Schlegerová D., Frantlová M., Slavík V., Tachezy R., Hamšíková E.:
Human papillomavirus infection (HPV) after the treatment of high–grade SIL of cervix uteri. In 10th World Congress of Cervical Pathology and Colposcopy.
Testa R., Jakob CA, Huguet JO (eds), Monduzzi Editore S.p.A., Bologna, Italy, pp 339–43, 1999.

Pluta M., Rob L., Citterbart K., Robová H., Kačírek J., Hřehorčák M., Schlegerová D., Frantlová M., Slavík V., Tachezy R., Hamšíková E.:
„Needle“ cone: new technique in the treatment of SIL–high lesions of the uterine cervix. In 10th World Congress of Cervical Pathology and Colposcopy.
Testa R., Jakob CA, Huguet JO (eds), Monduzzi Editore S.p.A., Bologna, Italy, pp 327–31, 1999.

Tachezy R., Hamšíková E., Hájek T., Mikyšková I., Šmahel M., Van Ranst M., Kaňka J., Havránková A., Rob L., Guttner V., Slavík V., Anton M., Kratochvíl B., Kotršová L., Vonka V.:
Human papillomavirus genotype spectrum in Czech Women: correlation of HPV DNA presence with antibodies against HPV-16, 18 and 33 virus like particles.
J. Med. Virol. 58, 378-386, 1999.
PMID: 10421405

Šmahel M., Sobotková E., Vonka V., Hamšíková E., Žák R., Kitasato H., Ludvíková V.:
DNA vaccine against oncogenic hamster cells transformed by HPV16 E6/E7 oncogenes and the activated ras oncogene.
Oncol. Rep. 6, 211-215, 1999.
PMID: 9864430

Hamšíková E., Ludvíková V., Tachezy R., Kovařík J., Břoušková L., Vonka V.:
Longitudinal follow-up of antibody response to selected antigens of human papillomaviruses and herpesviruses in patients with invasive cervical carcinoma.
Int. J. Cancer 86, 351-355, 2000.
PMID: 10760822

Di Lonardo A., Marcante ML, Poggiali F., Hamšíková E., Venuti A.:
Egg yolk antibodies against the E7 oncogenic protein of human papillomavirus type 16.
Arch. Virol. 146, 117–25, 2001.

Zehbe I., Tachezy R., Mytilineos J., Voglino G., Mikyšková I., Delius H., Marongiu A., Gissmann L., Wilander E., Tommasino M.:
Human papillomavirus 16 E6 polymorphisms in cervical lesions from different European populations and their correlation with human leukocyte antigen class II haplotypes.
Int. J. Cancer 94, 711-6, 2001.
PMID: 11745467

Šmahel M., Sobotková E., Bubeník J., Šímová J., Žák R., Ludvíková V., Hájková R., Kovařík J., Jelínek F., Povýšil C., Marinov J., Vonka V.:
Metastatic MHC class I-negative mouse cells derived by transformation with human papillomavirus type 16.
Br. J. Cancer 84, 374-380, 2001.
PMID: 11225590

Mikyšková R., Bubeník J., Mendoza L., Vonka V., Šmahel M., Šímová J., Jandlová T.:
Local cytokine treatment of HPV16-associated tumours results in reduction of their lung metastases.
Clin. Exper. Metastasis 18, 581-587, 2001.
PMID: 11688963

Šmahel M., Šíma P., Ludvíková V., Vonka V.:
Modified HPV16 E7 genes as DNA vaccine against E7-containing oncogenic cells.
Virology 281, 231-238, 2001.
PMID: 11277695

Němečková Š, Stránská R., Šubrtová J., Kutinová L., Otáhal P., Hainz P., Marešová L., Šroller V., Hamšíková E., Vonka V.:
Immune response to E7 protein of human papillomavirus type 16 anchored on the cell surface.
Cancer Immunol. Immunother. 51(2), 111–9, 2002.
PMID: 11904736

Tachezy R., Duson G., Rector A., Jenson AB, Sundberg JP, Van Ranst M.:
Cloning and genomic characterization of Felis domesticus papillomavirus type 1.
Virology 301, 313-21, 2002.
PMID: 12359433

Tachezy R., Rector A., Havelková M., Wollants E., Fiten P., Opdenakker G., Jenson B., Sundberg J., Van Ranst M.:
Avian papillomaviruses: the parrot Psittacus erithacus papillomavirus (PePV) genome has a unique organization of the early protein region and is phylogenetically related to the chaffinch papillomavirus.
BMC Microbiol. 2, 19, 2002.
PMID: 12110158

Tachezy R., Saláková M., Hamšíková E., Kaňka J., Havránková A., Vonka V.:
Prospective study on cervical neoplasia: presence of HPV DNA in cytological smears precedes the development of cervical neoplastic lesions.
Sex. Trans. Infections 79, 1-6, 2003.
PMID: 12794200

Švec A., Mikyšková I., Hes O., Tachezy R.:
Human papillomavirus infection of the epididymis and ductus deferens: an evaluation by nested polymerase chain reaction.
Arch. Pathol. Lab. Med. 127, 1471-4, 2003.
PMID: 14567721

Šmahel M., Šíma P., Ludvíková V., Marinov I., Pokorná D., Vonka V.:
Immunization with modified HPV16 E7 genes against mouse oncogenic TC-1 cell sublines with downregulated expression of MHC class I molecules.
Vaccine 21, 1125-1136, 2003.
PMID: 12559790

Rector A., Tachezy R., Van Ranst M.:
A sequence-independent strategy for detection and cloning of novel papillomaviruses using multiply primed rolling-circle amplification.
J. Virol. 78, 4993-4998, 2004.
PMID: 15113879

Klozar J., Klimák P., Kodet R., Saláková M., Šmahelová J., Hamšíková E., Tachezy R.:
HPV a riziko orálního a orofaryngeálního karcinomu.
Otorynolaryngologie 53,60-64, 2004.

Šmahel M., Pokorná D., Macková J., Vlasák J.:
Enhancement of immunogenicity of HPV16 E7 oncogene by fusion with E. coli beta-glucuronidase.
J. Gene Med. 6, 1092-1101, 2004.
PMID: 15386741

Tachezy R., Klozar J., Saláková M., Smith E., Turek L., Betka J., Kodet R., Hamšíková E.:
HPV and other risk factors of oral cavity/oropharyngeal cancer in the Czech Republic.
Oral Diseases 11(3), 182-186, 2005.

Rector A., Tachezy R., Van Doorslaer K., MacNamara T., Burk RD, Sundberg JP, Van Ranst M.:
Isolation and cloning of a papillomavirus from a North American porcupine by using multiply primed rolling-circle amplification: the Erethizon dorsatum papillomavirus type 1.
Virology 331, 449-56, 2005.
PMID: 15629787

Pokorná D., Macková J., Dušková M., Rittich Š, Ludvíková V., Šmahel M.:
Combined immunization with fusion genes of mutated E7 gene of human papillomavirus type 16.
J. Gene Med., 2005, in press.
PMID: 15712328

Smith, E.; Ritchie, J.; Pawlita, M.; Rubenstein, L.; Haugen, T.; Turek, L.; Hamšíková, E. :
Human papillomavirus seropositivity and risks of head and neck cancer.
Int. J. Cancer. Vol. 120, no. 4 (2006), s. 825–832.
Impact Factor: 4.700

Macková, J.; Stašíková, J.; Kutinová, L.; Mašín, J.; Hainz, P.; Hamšíková, E.; Šimšová, M.; Gabriel, P.; Šebo, P.; Němečková, Š. :
Prime/boost immunotherapy of HPV16-induced tumors with E7 protein delivered by Bordetella adenylate cyclase and modified vaccinia virus Ankara.
Cancer Immunol. Immunother. Vol. 55, no. 1 (2006), s. 39–46.
Impact Factor: 4.086

Tachezy, R.; Rob, L. :
Skrinink pro prevenci karcinomu děložniho hrdla v Česke republice.
Čas.Lek.čes. Roč. 146, č. 12 (2007), s. 939–944.
Impact Factor: 0.000

Klozar, J.; Zabrodsky, M.; Kodet, R.; Saláková, M.; Šmahelová, J.; Ludvíková, V.; Hamšíková, E.; Tachezy, R. :
Humánní papillomaviry v etiologii karcinomu ústní dutiny a orofaryngu.
Otorinolaryng. a Foniat.(Prague). Roč. 56, č. 2 (2007), s. 73–81.
Impact Factor: 0.000

Vonka, V.; Hamšíková, E. :
Usnesení Pracovní skupiny pro očkování proti lidským papillomavirům ze dne 12. 12. 2006.
Epidemiol.Mikrobiol.Imunol. Vol. 56, č. 2 (2007), s. 94–98.
Impact Factor: 0.000

Klozar, J.; Zabrodsky, M.; Mudrová, E.; Hamšíková, E.; Saláková, M.; Šmahelová, J.; Tachezy, R. :
The role of HPV as a risk and prognostic factor in head and neck.
Cent.Eur.J.Public Health. Roč. 16, č. S (2008), s. S40–S41.
Impact Factor: 0.000

Tachezy, R.; Hamšíková, E.; Šmahelová, J. :
Cervical cancer screening in the Czech Republic.
Cent.Eur.J.Public Health. Roč. 16, č. S (2008), s. S31–S32.
Impact Factor: 0.000

Pokorná D, Poláková I, Kindlová M, Dušková M, Ludvíková V, Gabriel P, Kutinová L, Muller M, Šmahel M.
Vaccination with human papillomavirus type 16-derived peptides using a tattoo device.
Vaccine 27, 3519–3529, 2009

Nicula FA, Anttila A, Neamtiu L, Zakelj MP, Tachezy R, Chil A, Grce M, Kesić V.
Challenges in starting organised screening programmes for cervical cancer in the new member states of the European Union.
Eur J Cancer 45(15), 2679-84, 2009

Saláková M, Němeček V, Tachezy R.
TTV and HPV co-infection in cervical smears of patients with cervical lesions.
BMC Infect Dis 9, 118, 2009

Klug SJ, Ressing M, Koenig J, Abba MC, Agorastos T, Brenna SM, Ciotti M, Das BR, Del Mistro A, Dybikowska A, Giuliano AR, Gudleviciene Z, Gyllensten U, Haws AL, Helland A, Herrington CS, Hildesheim A, Humbey O, Jee SH, Kim JW, Madeleine MM, Menczer J, Ngan HY, Nishikawa A, Niwa Y, Pegoraro R, Pillai MR, Ranzani G, Rezza G, Rosenthal AN, Roychoudhury S, Saranath D, Schmitt VM, Sengupta S, Settheetham-Ishida W, Shirasawa H, Snijders PJ, Stoler MH, Suárez-Rincón AE, Szarka K, Tachezy R, Ueda M, van der Zee AG, von Knebel Doeberitz M, Wu MT, Yamashita T, Zehbe I, Blettner M.
TP53 codon 72 polymorphism and cervical cancer: a pooled analysis of individual data from 49 studies.
Lancet Oncol 10 (8), 772-84, 2009.

Tachezy R, Klozar J, Rubenstein L, Smith E, Saláková M, Šmahelová J, Ludvíková V, Rotnáglová E, Kodet R, Hamšíková E.
Demographic and risk factors in patients with head and neck tumors.
J Med Virol 81 (5), 878-87, 2009

Dennis LK, Coughlin JA, McKinnon BC, Wells TS, Gaydos CA, Hamšíková E, Gray GC.
Sexually transmitted infections and prostate cancer among men in the U.S. military.
CEBP 18 (10), 2665-71, 2009

Smith EM, Pawlita M, Rubenstein LM, Haugen TH, Hamšíkova E, Turek LP.
Risk Factors and Survival by HPV-16 E6 and E7 Antibody Status in Human Papillomavirus Positive Head and Neck Cancer.
IJC, epub ahead of print, Oct 28 2009,

Hrušková V, Morávková A, Babiarová K, Ludvíková V, Fric J, Vonka V, Forstová J.
Bcr-Abl fusion sequences do not induce immune responses in mice when administered in mouse polyomavirus based virus like particles.
Int J Oncol 35 (6), 1247-56, 2009

Lučanský V, Sobotková E, Tachezy R, Dušková M, Vonka V.
DNA vaccination against bcr-abl-positive cells in mice.
Int J Oncol 35 (4), 941-51, 2009

Sobotková E, Dušková M, Tachezy R, Petráčková M, Vonka V.
Combined chemo- and immunotherapy of tumors induced in mice by bcr-abl-transformed cells.
Oncol Rep 21 (3), 793-9, 2009

Smith, E.M.;Pawlita,M.; Rubenstein,L.M.;Haugen, T.H.; Hamšíková,E.; Turek,L.P.
Risk factors and survival by HPV-16 E6 and E7 antibody status in human papillomavirusm positive head and neck cancer.
Int. J. Cancer.Vol 127, no. 1 (2010) s.111-117.

Smith, E.M.;Pawlita,M.; Rubenstein,L.M.;Haugen, T.H.; Hamšíková,E.; Turek,L.P.
Tobacco and alcohol use increases the risk of both HPV-associated and HPV-independent head and neck cancers.
Cancer Causes Control. Vol.21, no.9 (2010), s.1369-1378.

Hrbáček, J.; Heráček,J.; Eis, V.; Hamšíková, E.; Tachezy,R.; Urban,M.
Incidence, diagnostika a léčba karcinomu prostaty u HIV pozitivních pacientů.
Čes. Urol. Roč.14,č.1 (2010) s.14-23.

Hrbáček, J.; Konopásek, P.; Eis,V.;Hamšíková E.;Tachezy,R.; Pokorný, J.;El-Balouly K.; Urban,M.; Heráček,J.
Urologické komplikace HIV/AIDS
Čas. Lék. Čes. Roč. 149, č.3 (2010), s. 115-119.

Klozar,J.; Tachezy,R.; Rotnáglová, E.; Košlabová, E.; Saláková,M.; Hamšíková,E.
Human papillomavirus in head and neck tumors: epidemiological, molecular and clinical aspects.
Wien. Med. Wochenschr. Vol.160, no.11-12 (2010), s 305-309.

Rotnáglová, E.; Tachezy,R.; Saláková, M.; Košlabová, E.; Šmahelová,J.; Hamšíková,E; Ludvíková, V.; Klozar, J.
Vztah lidských papillomavirů a etiologie karcinomů patrových mandlí.
Otorinolaryng. a Foniat. (Prague), Roč. 59.č.1 (2010) s. 32-37.

Smith, E.M.; Parker, M.A.;Rubenstein, L.M.; Haugen,T.H.; Hamšíková,E.; Turek,L.P.
Evidence for vertical transmission of HPV from mothers to infants.
Infect. Dis. Obstet. Gynecol. ( 2010), art. No 326369.

Prevalence and genetic heterogeneity of SEN virus genotypes D and H in blood donors from Central and Western Europe and West Africa.
Thom K, Cleland A, Saláková M, Candotti D, Petrík J.
Transfus Med. 2010 Sep 30. doi: 10.1111/j.1365-3148.2010.01039.x. [Epub ahead of print]

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